Apply for a Cannabis Business Permit

Cannabis Business Permits are issued by the Cambridge Inspectional Services Department (ISD). Anyone seeking to open a Cannabis Retail Store or operate as a Marijuana Treatment Center (MTC), Cultivator, Product Manufacturer, Microbusiness, Courier Establishment, Delivery Operator Establishment, and/or Transporter in Cambridge must obtain a Cannabis Business Permit. The Cannabis Business Permit must be obtained prior to final approval from the Commonwealth of Massachusetts Cannabis Control Commission (MA CCC) for a Marijuana Establishment License.

In addition to the Cannabis Business Permit, Cannabis Production Facilities are required to secure a Special Permit.

These local requirements are in addition to any state requirements for the Marijuana Establishment License issued from the MA CCC. Information about the state Marijuana Establishment License process can be found on the Massachusetts Cannabis Control Commission (MA CCC) website

How to Start

Note: On June 9, 2025 the Cambridge City Council ordained changes to the Cannabis Business Permitting Ordinance which resulted in the Host Community Agreement (HCA) no longer being required prior to securing a Marijuana Establishment License from the MA CCC. Subsequently, the application for the Cannabis Business Permit has expanded and now includes some additional questions.

The information below reflects those changes. If you are a cannabis business with questions about what these changes means for your business, please contact staff in the Economic Opportunity and Development Division of CDD (see below).

Pre-Application Steps

1. Meet with staff in the Community Development Department (CDD) – Contact Christina DiLisio in the Economic Opportunity and Development Division of CDD at cdilisio@cambridgema.gov or 617/349-4601 to request a meeting and learn more about the requirements and process for the Cannabis Business Permit.
2. Research the Marijuana License Establishment process –Information about the application process for a Marijuana Establishment License with the MA CCC can be found on the MA CCC website.
3. Hold Community Meeting – The MA CCC requires Marijuana Establishment License applicants to host a public meeting. Upon request, staff in CDD can assist with generating abutter’s lists as well as provide contact information for area business and/or neighborhood associations.   

Local Approval 

4. Cannabis Business Permit Applicant Review - Submit a complete Cannabis Business Permit application via the online Viewpoint portal. Staff in the Community Development Department will determine eligibility to proceed. The Cannabis Business Permitting Ordinance contains information regarding which individuals are presently eligible for review. Please consult the Cannabis Business Priority A Applicant Documentation [PDF]  to identify which forms of supporting documentation you will be required to provide at the time of application.  At this time ISD will confirm compliance with the zoning requirements for Cannabis Businesses found at Section 11.800 of the Cambridge Zoning Ordinance.
5. Secure a Special Permit (only required for Cannabis Production Facility) – Submit a complete Special Permit Application to the Cambridge Planning Board. A hearing will be held and approval of a Special Permit will be granted or denied based on compliance with zoning criteria.
6. Cannabis Business Permit Business Operations Review – Complete the Cannabis Business Permit application by providing any remaining information about anticipated business operations. Please consult the Frequently Asked Questions (FAQ) Document for information about which pieces of information regarding anticipated business operations are required at the time of application.
7. Cannabis Business Permit Issuance - Submit Provisional MA CCC Marijuana Establishment License to ISD. Following receipt, and sign-off from all necessary City of Cambridge departments, ISD will issue a Cannabis Business Permit.
8. Building Permit – Following City review of applicant's Provisional MA CCC Marijuana Establishment License, Special Permit (if required), and Cannabis Business Permit, ISD issues Building Permit. 
9. Certificate of Occupancy – Following City review of applicant's Provisional MA CCC Marijuana Establishment License, Special Permit (if required), and Cannabis Business Permit, ISD issues Certificate of Occupancy.

State Approval

10. Information about the approval process for a Marijuana Establishment License with the MA CCC, including information about the Provisional Marijuana Establishment License, the Final Marijuana Establishment License, and the Commence Operations notice can be found on the MA CCC website.